
Probiotics designed to survive the journey
Ortho Molecular Products probiotics are developed to maintain strain viability across the full digestive process. Featuring clinically researched strains selected for tolerance to gastric acid, bile, and enzymatic conditions, along with advanced delivery designed to support survival through GI transit, these formulas help promote consistent delivery of live microorganisms to the intestine and support a healthy microbiome.
Our advanced formulation and protective delivery help preserve potency through digestion, so the organisms your patients take are the organisms that reach the gut.
Our probiotics are formulated for specific applications, from general maintenance to advanced support. Use this chart to help you decide when to use each product with your patients.
| Product | Bottle | Use | CFU++ | ||
Advanced | Probiotic 225
Buy 12, Get 2 FREE Code: BIOTIC12 | ![]() |
| 225 Billion | |
| Ortho Biotic 100
Buy 12, Get 2 FREE Code: BIOTIC12 | ![]() |
| 100 Billion | ||
Support | Ortho Biotic
Buy 12, Get 2 FREE Code: BIOTIC12 | ![]() |
| 20 Billion + 3 Billion S. boulardii | |
| Saccharomyces boulardii | ![]() |
| 5 Billion | ||
| Ortho Biotic Women's | ![]() |
| 2 Billion | ||
| ++Colony Forming Units |
With approximately 500 different subspecies of bacteria contained in the human GI tract, biodiversity and balance in the microbiome are likely more important than the prominence of only a few species. Certain bacterial subspecies are known to reside only in very particular parts of the GI tract. Because of this, efficacious probiotic supplementation provides a broad number of probiotic strains. Each strain has a slightly different range of metabolic and protective functions and may occupy a different micro-environmental niche within the GI tract. This multi-strain approach allows robust support for more commensal organisms along the entire GI tract.
The phylogenetic tree below represents the diversity and symbiotic nature of probiotics, which mimics the diversity of the microbiome. We select strains from each genetically unique group, providing ideal probiotic potential and unmatched efficacy in formulation.
We formulate probiotic supplements using proven science and manufacturing practices that ensure the highest efficacy. Probiotics are live organisms and, to be effective, they must be shelf-stable through the expiration date and precisely delivered to the intestinal tract, where they can have maximum benefit. BioShield® technology is an innovative manufacturing process developed to ensure consistent and reliable results. The microorganisms in our probiotics are protected, sealed and freeze dried away from moisture, heat, light and oxygen. This allows the bacteria to remain dormant until they are exposed to moisture in the GI tract. This innovative process also guarantees probiotic potency at expiration without the need for refrigeration.
| B. bifidum Bb-02 | B. animalis subsp. Lactis Bi-04 | L. acidophilus La-14 | L. paracasei Lpc-37 | L. plantarum Lp-115 | L. rhamnosus GG | Saccharomyces boulardii | |
|---|---|---|---|---|---|---|---|
| Survival | |||||||
| Acid Tolerance | ★★★★★ | ★★★★★ | ★★★★★ | ★★★★☆ | ★★★★★ | ★★★★★ | ★★★★★ |
| Bile Tolerance | ★★★★☆ | ★★★★★ | ★★★★★ | ★☆☆☆☆ | ★★★★★ | ★★★★★ | ★★★★★ |
| Pepsin Resistance | NA | NA | ★★★★☆ | ★☆☆☆☆ | ★★★☆☆ | ★★★★☆ | ★★★☆☆ |
| Pancreatin Tolerance | NA | NA | ★★★★☆ | ★★★★☆ | ★★★★☆ | ★★★★☆ | ★★★★☆ |
| Antibiotic Tolerance | |||||||
| Amoxicillin | S | S | S | S | S | R | R |
| Ampicillin | I | S | S | S | S | S | R |
| Penicillin G | S | S | S | S | R | S | R |
| Ciprofloxacin | R | R | R | R | R | R | R |
| Clindamycin | S | S | I | S | S | S | R |
| Erythromycin | I | S | S | S | I | S | R |
| Vancomycin | R | R | S | R | R | R | R |
| Tetracycline | R | R | R | S | R | S | R |
| Gentamycin | R | R | R | R | R | R | R |
| Neomycin | R | R | R | R | R | R | R |
| Streptomycin | R | R | R | R | R | R | R |
| Sulfamethoxazole | R | R | R | R | R | R | R |
| Trimethoprim | R | S | R | R | R | R | R |
| Probiotics from Ortho Molecular Products |
|||||||
| Ortho Biotic® | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
| Ortho Biotic® 100 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
| Probiotic 225 | ✓ | ✓ | ✓ | ||||
| Saccharomyces boulardii | ✓ | ||||||
*Cannot be combined with any other offer, promotion or discount. Applies to SKU 527030CAN, 474030CAN and 470015CAN. Applies to Ortho Molecular Products brand only. Qualifying orders must include 12 eligible products to receive 2 free. Offer expires 9/30/2026.